09:00-12:30 Lab sessions

12:30-13:30 Lunch 

13:30-18:15 Lab sessions



09:00-09:30 Registration

09:30-10:00 Welcome

10:00-10:45 Local and descending modulation of spinal dorsal horn circuits involved in nociceptive processing
Peter Szucs
, University of Debrecen, Dept. Anatomy, Histology and Embryology / MTA-DE-NAP B-Pain Control Research Group, Hungary

10:45-11:15 Coffee break

11:15-12:00 Lumbar pain. Interventional approach.
David Abejón, MD, Hospital Universitario Quironsalud Madrid, Spain

12:00-12:15 Axonal outgrowth cues hidden in the osteoclasts secretome
Estrela Neto, i3S/ INEB, Faculdade de Medicina, Universidade do Porto, Portugal

12:15-12:30 Non-coding RNA: a new strategy to improve bone regeneration
Maria Inês Almeida, i3S/ INEB, Portugal

12:30-12:45 Bio-modeling breast cancer-bone metastases in microfluidic systems: a novel 3D approach
Francisco Conceição, i3S/ INEB, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Porto, Portugal

12:45-13:00 Temporal regulation of systemic miRNA profile upon bone injury
Andreia Machado da Silva, i3S/ INEB, ICBAS, Portugal

13:00-13:15 Neurotrophic potential of Mesenchymal Stem Cells throughout osteoblast differentiation and under different ECM-like microenvironments
Luís Leitão, i3S/ INEB, ICBAS, Portugal

13:15-14:15 Lunch

14:15-14:45 Speed talks [1 to 6]

14:45-15:45 Poster Session

15:45-16:15 Coffee break

16:15-17:00 Advances in vertebral augmentation procedures
Pedro Santos Silva
, Centro Hospitalar São João, Porto, Portugal



09:00-09:45 Cell delivery and cell recruitment – the role of supporting hydrogel for repair and regeneration
Sybille Grad,
AO Research Institute Davos, Switzerland

09:45-10:30 Stem Cells and Biomaterials for the Regenerative Medicine of Intervertebral Disc «When Developmental Biologists meet Tissue Engineers»
Jérôme Guicheux

10:30-11:00 Coffee break

11:00-11:45 Degenerative lumbar disease – A good asset for investment in future research?
José Guimarães Consciência
, Orthopedic Department at S. F. Xavier – CHLO Central Hospital/ NOVA Medical School – Lisbon NOVA University, Portugal

11:45-12:00 MSCs immunomodulatory role in degenerated IVD
Graciosa Teixeira, i3S/ INEB, ICBAS, Portugal and University of Ulm, Germany

12:00-12:15 Nucleus Pulposus age-associated matrix profiling
Joana Caldeira, i3S/ INEB/ Ipatimup, Portugal

12:30-13:45 Lunch

13:45-14:00 Group photo

14:00-14:30 Speed talks [7 to 12]

14:30-15:30 Poster Session

15:30-16:00 Coffee break

16:00-16:45 In-vitro models, finite-element models and animal models in spine Research
Hans-Joachim Wilke, Institute of Orthopaedic Research and Biomechanics, Trauma Research Center Ulm, University Hospital Ulm, Germany

20:00 Summer School Dinner at Árvore Restaurant



09:00-09:45 Zoom out: Clinical Practice in SCI Rehabilitation
Maria Cunha, Centro de Reabilitação do Norte, Santa Casa da Misericordia do Porto, Portugal

09:45-10:30 Anti-Nogo on the go. From bench to bed side with a neurite growth enhancing therapy for spinal cord injury and stroke
Martin Schwab, Brain Research Institute, University of Zurich and Department of Health Science and Technology, Swiss Federal Institute of Technology Zurich, Switzerland

10:30-11:00 Coffee break

11:00-11:45 Shaping SCI Regeneration trough ECM-like Hydrogels and Stem Cells Secretome
António Salgado, Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Portugal

11:45-12:00 Exploring tissue engineering to dissect astrocyte-oligodendrocyte crosstalk in the context of demyelinating diseases
Eva Carvalho, i3S/ INEB, Portugal

12:00-12:15 Functionalization of fibrin hydrogels with α6β1 integrin-binding adhesive peptides for delivery of pluripotent stem cell-derived neural stem/progenitors
Ana Rita Bento, i3S/ INEB, Faculdade de Engenharia, Universidade do Porto, Portugal

12:15-12:30 Bladder instillation of Resiniferatoxin during the spinal shock prevents high intravesical pressures after spinal cord injury
Raquel Oliveira, Faculdade de Medicina, Universidade do Porto, Portugal

12:30-14:00 Lunch

14:00-14:45 Linking Wnt pathway with bone mineralization, mechanical properties and fracture risk in osteoporosis
Ana Maria Rodrigues, EpiDoc Unit at CEDOC, the Chronic Diseases Research Centre at Nova Medical School, Portugal

14:45-15:30 The value of a chronic pain unit with clinical investigation 
Margarida Barbosa, Centro Hospitalar São João, Porto, Portugal

15:30-16:00 Coffee break

16:00-16:45 Low Back Pain Diagnosis: the Mine Field
Luis Barroso, CUF Descobertas Hospital, Lisbon, Portugal

16:45-17:45 Awards and Closing Session